P-164. The SCID (severe combined immunodeficiency) mouse: an experimental model for endometriosis
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چکیده
منابع مشابه
Severe combined immunodeficiency (SCID) mouse modeling of P-glycoprotein chemosensitization in multidrug-resistant human myeloma xenografts.
We have established a reproducible in vivo model of human multiple myeloma in the severe combined immunodeficiency (SCID) mouse using both the drug-sensitive 8226/S human myeloma cell line and the P-glycoprotein-expressing multidrug-resistant 8226/C1N subline. As demonstrated previously, the SCID mouse is well suited as a model for myeloma because: (a) human SCID xenografts are readily attained...
متن کاملSevere Combined Immunodeficiency (SCID) Mouse Modeling of P-Glycoprotein Chemosensitization in Multidrug-resistant Human Myeloma Xenografts1
We have established a reproducible in vivo model of human multiple myeloma in the severe combined immunodeficiency (SCID) mouse using both the drug-sensitive 8226/S human myeboma cell line and the P-glycoproteinexpressing multidrug-resistant 8226/C1N subline. As demonstrated previously, the SCID mouse is well suited as a model for myeloma because: (a) human SCID xenografts are readily attained;...
متن کاملNewborn screening for severe combined immunodeficiency (SCID): a review.
Because prompt intervention may prevent complications, early diagnosis is important in many inherited metabolic diseases. Early diagnosis of Severe Combined Immunodeficiency (SCID) is critical - because chances for successful treatment are highest for infants who have not yet experienced severe opportunistic infections. SCID is a rare disease that can be detected in newborn infants (i.e., those...
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We report that the spirochete B. burgdorferi induces progressive polyarthritis and carditis in mice with severe combined immunodeficiency syndrome (scid) but not in normal C.B-17 mice. The onset and severity of the disease were dependent on (a) the viability; (b) the infectivity; and (c) the dose of inoculated B. burgdorferi organisms. Infective spirochetes were isolated from both blood and joi...
متن کاملgenetic monitoring for severe combined immunodeficiency disease (scid) carriers in arabian horses of iran
scid is a lethal genetic autosomal recessive disorder that has been observed in humans, dogs, mice, and horses. affected animals are incapable of generating specific antigens for immune responses needed to protect them from infectious diseases. the frequency of affected recessive allele varies in different regions so that the outcome of normal breeding with carriers of recessive alleles is diff...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/14.suppl_3.223